ClustIRR - Clustering of immune receptor repertoires
ClustIRR clusters immune receptor repertoires (IRRs), and identifies groups of T or B cell receptors (TCRs or BCRs) with possibly similar specificity directly from the sequences of their complementarity determining regions. ClustIRR uses graphs to visualize the specificity structures of IRRs.
Last updated 23 days ago
clusteringimmunooncologysinglecellsoftwareclassification
2.27 score 59 dependenciesIgGeneUsage - Differential gene usage in immune repertoires
Detection of biases in the usage of immunoglobulin (Ig) genes is an important task in immune repertoire profiling. IgGeneUsage detects aberrant Ig gene usage between biological conditions using a probabilistic model which is analyzed computationally by Bayes inference. With this IgGeneUsage also avoids some common problems related to the current practice of null-hypothesis significance testing.
Last updated 4 months ago
differentialexpressionregressiongeneticsbayesianbiomedicalinformaticsimmunooncologymathematicalbiology
6 stars 2.00 score 85 dependenciesscBubbletree - Quantitative visual exploration of scRNA-seq data
scBubbletree is a scalable and quantitative method for the visual exploration of scRNA-seq data that preserves biologically meaningful properties, including local and global cell distances and cell density distributions across samples. It effectively addresses overplotting issues and enables the visualization of diverse cell attributes derived from multiomic single-cell experiments. Furthermore, scBubbletree is user-friendly and easily integrates with popular scRNA-seq data analysis approaches, facilitating comprehensive and intuitive data interpretation.
Last updated 5 days ago
visualizationclusteringsinglecelltranscriptomicsrnaseq
5 stars 1.51 score 162 dependencies